AbbVie Inc. Announces VERONA Trial Results: Venetoclax Combination Falls Short on Improving Overall Survival in Higher-Risk Myelodysplastic Syndrome

Reuters
16 Jun
AbbVie Inc. Announces VERONA Trial Results: Venetoclax Combination Falls Short on Improving Overall Survival in Higher-Risk Myelodysplastic Syndrome

AbbVie Inc. has announced an update on their global Phase 3 VERONA trial, which assessed the efficacy of venetoclax in combination with azacitidine for the treatment of newly diagnosed higher-risk myelodysplastic syndrome (HR-MDS). The trial did not achieve its primary endpoint of overall survival, with a hazard ratio of 0.908 and a p-value of 0.3772. There were no new safety signals observed during the study. Results from the VERONA trial are scheduled to be presented at a future medical congress or publication. This outcome does not affect any of the currently approved indications for venetoclax. More detailed information about the trial can be accessed on ClinicalTrials.gov.

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