智通财经APP获悉，来凯医药-B(02105)再涨超4%，截至发稿，涨4.2%，报17.38港元，成交额4544.15万港元。
消息面上，来凯医药近日公布，集团已就自主研发的LAE103(一种针对ActRIIB的单克隆抗体)，向美国食品药品监督管理局(FDA)递交新药临床试验申请(IND)，潜在用于治疗肌少性肥胖症及肌肉相关疾病患者。集团计划分别评估靶向ActRIIA与ActRIIB受体的单克隆抗体在人体中的疗效及安全性。
太平洋证券发报指，LAE102国内MAD研究（皮下给药）和美国1期均已启动，预计25H2数据读出。LAE102的中国I期MAD研究已启动，评估皮下给药LAE102在60名超重/肥胖受试者中的安全性、耐受性、PD和PK，预计25Q3数据读出。海外临床方面，礼来已启动美国1期临床，计划入组32例健康绝经后女性，通过皮下和静脉单次递增剂量给药，5月完成首位受试者给药，计划于9月完成主要研究阶段。
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