金融界2025年7月12日消息，国家知识产权局信息显示，深圳连续制药科技有限公司;哈尔滨工业大学（深圳）（哈尔滨工业大学深圳科技创新研究院）申请一项名为“一种氟代芳烃的加氢脱氟方法”的专利，公开号CN120289263A，申请日期为2025年04月。
专利摘要显示，本发明涉及一种以乙醇为绿色还原剂和溶剂制备芳基化合物的方法。本发明在钯催化剂条件下，将氟代芳烃与碱和醇混合，发生脱氟氢化反应，其中醇包括乙醇和/或异丁醇。本反应中乙醇和/或异丁醇同时作为溶剂和还原剂，无需额外加入还原剂，避免了氢气、氢化铝锂等危险还原剂的使用。该催化剂体系底物适用性优良，对于常见的供电子基、吸电子基、杂环都能很好兼容，最高收率可达99％。此外，该反应体系可在分析纯乙醇以及空气中进行，无需复杂的无氧操作，便于大规模工业应用。
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