【歌礼制药-B(01672.HK):歌礼脂肪靶向、每月一次注射的小分子THRβ激动剂ASC47 联合司美格鲁肽治疗肥胖症

智通财经
Jul 15, 2025
【歌礼制药-B(01672.HK):歌礼脂肪靶向、每月一次注射的小分子THRβ激动剂ASC47 联合司美格鲁肽治疗肥胖症的美国临床研究完成所有受试者给药】智通财经APP讯,歌礼制药-B(01672.HK)发布公告,评估超长效皮下注射ASC47单次给药联合司美格鲁肽在不伴有2型糖尿病的肥胖受试者中的安全性、耐受性以及在第29天的初步疗效的随机、双盲、安慰剂对照研究(ASC47-103研究, NCT06972992)已于近期完成所有28例受试者给药。28例受试者入组于两个月内快速完成。ASC47-103研究在美国开展,共设3个队列,受试者接受ASC47单剂量递增(10毫克、30毫克和60毫克)或注射等量(volume-matched)安慰剂。各队列受试者还接受四次司美格鲁肽(0.5毫克,每周一次)给药。

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