Compugen Ltd. Begins Dosing in Global COM701 Platform Trial for Platinum Sensitive Ovarian Cancer

Reuters

Jul 21

Compugen Ltd. Begins Dosing in Global COM701 Platform Trial for Platinum Sensitive Ovarian Cancer

Compugen Ltd. has announced the dosing of the first patient in a global randomized sub-trial of the MAIA-ovarian adaptive platform trial. This trial is evaluating the maintenance therapy with COM701, a potential first-in-class anti-PVRIG antibody, in patients with relapsed platinum sensitive ovarian cancer. The trial is supported by a strong biological rationale and previous clinical data, which demonstrated that COM701 in combination with PD-1 and TIGIT blockade achieved durable responses and was well tolerated. The interim analysis for sub-trial 1 is expected to be conducted in the second half of 2026. Results from this analysis will potentially inform a registration path for COM701 monotherapy and explore opportunities to combine it with other agents.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Compugen Ltd. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission (Ref. ID: 0001178913-25-002420), on July 21, 2025, and is solely responsible for the information contained therein.

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Begins Dosing in Global COM701 Platform Trial for Platinum Sensitive Ovarian Cancer","media":"Reuters","content":"<html xmlns=\"http://www.w3.org/1999/xhtml\" xmlns:newsg2=\"http://iptc.org/std/nar/2006-10-01/\" xmlns:xhtml=\"http://www.w3.org/1999/xhtml\"><head><title>\n      Compugen Ltd. Begins Dosing in Global COM701 Platform Trial for Platinum Sensitive Ovarian Cancer\n    </title></head><body><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n        Compugen Ltd. has announced the dosing of the first patient in a global randomized sub-trial of the MAIA-ovarian adaptive platform trial. This trial is evaluating the maintenance therapy with COM701, a potential first-in-class anti-PVRIG antibody, in patients with relapsed platinum sensitive ovarian cancer. 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Begins Dosing in Global COM701 Platform Trial for Platinum Sensitive Ovarian Cancer\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1032215980\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Reuters </p>\n<p class=\"h-time\">2025-07-21 19:01</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<html xmlns=\"http://www.w3.org/1999/xhtml\" xmlns:newsg2=\"http://iptc.org/std/nar/2006-10-01/\" xmlns:xhtml=\"http://www.w3.org/1999/xhtml\"><head><title>\n      Compugen Ltd. 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ID: 0001178913-25-002420), on July 21, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4139","symbol_name":"生物科技","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250721:nNDL4Nr6CP:1","article_id":"2553476655","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2553476655","pubTimestamp":1753095675,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Compugen Ltd. has announced the dosing of the first patient in a global randomized sub-trial of the MAIA-ovarian adaptive platform trial. 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