【券商聚焦】花旗:新一代免疫肿瘤治疗药物有望重塑癌症免疫治疗格局 上调多支生物科技股目标价

金吾财讯
Jul 28, 2025

金吾财讯 | 花旗发报指,新一代免疫肿瘤治疗药物,如双特异性或三特异性PD-1/VEGF、PD-1/IL-2、PD-1/VEGF/CTLA4等,有望重塑癌症免疫治疗的格局。预计这类药物的潜在市场规模可超过620亿美元。花旗表示,康方生物(09926)的ivonescimab在HARMONi-2/HARMONi-6试验中显示具统计学意义及临床意义的无进展生存期改善,以及令人鼓舞的中期总生存期数据。信达生物(01801)的IBI363在IO治疗的非小细胞肺癌及冷肿瘤中也显示出令人鼓舞的数据。花旗指出,关键免疫疗法产品如Keytruda和Opdivo的专利将于2028年到期,跨国药企需要补充新药以维持市场地位和收入。默沙东、百时美施贵宝辉瑞已引进新一代免疫疗法候选药物,该行认为其他制药公司仍在积极寻找这领域的资产。基于上述分析,花旗上调多只生物科技股目标价及评级:给予康方生物“买入”评级,目标价由98港元上调至185港元;维持信达生物“买入”评级,目标价由90港元上调至105港元;维持三生制药(01530)“买入”评级,目标价由21港元上调至36港元;维持君实生物(01877)“买入/高风险”评级,目标价由17港元上调至32港元;维持中国生物制药(01177)“买入”评级,目标价由6.20港元上调至8.80港元。

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