Janux Therapeutics Inc. recently held an R&D Day presentation, highlighting multiple near-term, high-value opportunities in cancer and inflammation and immunology (I&I). Their clinical programs include JANX007, currently in Phase 1b dose expansion trials for metastatic castration-resistant prostate cancer (mCRPC), and JANX008, undergoing Phase 1a evaluation for various solid tumor settings. The development pipeline features promising candidates such as PSMAxCD28-TRACIr, with an IND anticipated in the first half of 2026, and TROP2xCD3-TRACTr, with IND-enabling activities planned for the second half of 2025. Additionally, the CD19-ARM program presents potential in autoimmune diseases and hematologic oncology. The company reports a robust cash position of $1.01 billion as of March 2025, ensuring financial runway through significant clinical milestones. You can access the full presentation through the link below.
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