智通财经APP获悉,三生制药(01530)午前涨近3%,截至发稿,涨2.46%,报29.15港元,成交额6.39亿港元。
消息面上,近日,三生制药公布,公司与辉瑞就PD-1/VEGF双特异性抗体(SSGJ-707)订立的许可协议之所有先决条件已达成,许可协议自7月24日起生效。招银国际指出,辉瑞计划快速推进707在全球的III期临床试验,评估其单药及联用化疗、ADCs等联合疗法的潜力。辉瑞拥有丰富的临床资源和先进的ADC药物储备,如PADCEV、sigvotatug vedotin和PDL1V,这些都将有助于加速707的开发进程。
该行认为,707具备多重差异化特征,具有潜在同类最佳的抗血管生成活性及对PD-1的高亲和力,其四价结构和“链式联动”效应可实现更优的VEGF与PD-1协同结合,增强抗肿瘤活性并改善安全性和耐受性。在ASCO上公布的数据显示,在34例10mg/kg Q3W患者中,cORR达64.7%,展示了深度和持久的疾病缓解效果。
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