Incyte Projects 2025 Jakafi net product revenues Of $3B-$3.05B Compared To Prior Guidance Of $2.95B-$3B

Benzinga
Jul 29, 2025

2025 Financial Guidance

Incyte's guidance for the fiscal year 2025 is summarized below. Incyte is raising its revenue guidance for Jakafi to account for higher demand in the first half of 2025. Incyte is also raising its revenue guidance for other oncology products, to reflect the strength of the Niktimvo launch, higher demand for Zynyz in the first half of the year and the positive impact of foreign currency exchange rates. Incyte is updating its cost of product revenues guidance to reflect the reduction in the Jakafi royalty rate payable to Novartis, as a result of the contract dispute settlement. Furthermore, Incyte is updating its expense guidance for research and development to reflect the increase due to upfront and ongoing expenses related to new collaborations with Genesis and Biotheryx.

 CurrentPrevious
Jakafi net product revenues$3,000 - $3,050 million$2,950 - $3,000 million
Opzelura net product revenuesUnchanged$630 - $670 million
Other oncology net product revenues(1)$500 - $520 million$415 - $455 million
GAAP Cost of product revenues8.0% - 9.0% of net product revenues8.5% - 9.0% of net product revenues
Non-GAAP Cost of product revenues(2)7.0% - 8.0% of net product revenues7.5% - 8.0% of net product revenues
GAAP Research and development expenses$1,965 - $1,995 million$1,930 - $1,960 million
Non-GAAP Research and development expenses(3)$1,815 - $1,840 million$1,780 - $1,805 million
GAAP Selling, general and administrative expensesUnchanged$1,280 - $1,310 million
Non-GAAP Selling, general and administrative expenses(3)Unchanged$1,160 - $1,185 million

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