智通财经APP获悉，8 月 4 日，ClinicalTrials.gov 官网显示，诺华(NVS.US)登记了一项英克司兰钠的 III 期临床，旨在评估急性冠状动脉综合征(ACS)患者住院早期开始英克司兰钠治疗的疗效和安全性。这是一项多中心、随机、双盲、安慰剂对照研究，受试者为近期发生急性冠状动脉综合征(ACS)的患者，包括 ST 段抬高型心肌梗死(STEMI)和非 ST 段抬高型心肌梗死(NSTEMI)的患者。
英克司兰钠是全球首款获批的 PCSK9 siRNA 药物，于 2020 年、2021 年分别获欧盟、FDA 批准上市，用于治疗成人高胆固醇血症及混合性血脂异常，证明了小核酸药物在慢病领域的治疗潜力。
截至目前，该药已经在欧盟获批 4 项适应症，在美国获批 3 项适应症，在中国获批 4 项适应症。
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