诺华制药(NVS.US)抗BAFF-R单抗两项III期研究成功

智通财经
Aug 11

智通财经APP获悉,8月11日,诺华制药(NVS.US)宣布Ianalumab(VAY736)治疗活动性干燥综合征的两项III期研究(NEPTUNUS-1和NEPTUNUS-2)取得了积极结果。该药物有望成为干燥综合征领域首个靶向治疗药物。

Ianalumab是诺华收购(MorphoSys)获得的一款靶向B淋巴细胞活化因子受体(BAFF-R)的全人源单抗,具有耗竭B细胞和抑制BAFF-R的双重作用机制,可用于治疗干燥综合征、免疫性血小板减少症(ITP)、系统性红斑狼疮(SLE)等多种自免疾病。该药物是首个完成III期研究的抗BAFF-R抗体。

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