European equities traded in the US as American depositary receipts were edging lower late Friday morning, declining 0.17% to 1,514.13 on the S&P Europe Select ADR Index, which is up 1.8% for the week.

From continental Europe, the gainers were led by biopharmaceutical company Cellectis (CLLS) and internet browser company Opera (OPRA), which rose 2.5% and 2.2% respectively. They were followed by telecommunications company Nokia (NOK) and pharmaceutical company Novo Nordisk (NVO), which were up 2.1% and 1.7% respectively.

The decliners from continental Europe were led by accommodations booking site trivago (TRVG) and biopharmaceutical company argenx (ARGX), which fell 0.9% and 0.7% respectively. They were followed by internet browser company Criteo (CRTO) and software firm SAP (SAP), which were down 0.4% and 0.1% respectively.

From the UK and Ireland, the gainers were led by biopharmaceutical companies Akari Therapeutics (AKTX) and Amarin (AMRN), which increased 4.1% and 2.7% respectively. They were followed by pharmaceutical company pharmaceutical company Silence Therapeutics (SLN) and ming company BHP (BHP), which advanced 1.5% and 1.3% respectively.

The decliners from the UK and Ireland were led by biotech firm Trinity Biotech (TRIB) and software company Endava (DAVA), shed 18% and 3.4% respectively. They were followed by biopharmaceutical company Adaptimmune Therapeutics (ADAP) and financial services company HSBC (HSBC), which lost 2.7% and 1.8% respectively.