Enlivex Therapeutics Announces Positive Results from Phase I/II Trial of Allocetra™ for Knee Osteoarthritis Treatment

Reuters
Aug 18
Enlivex <a href="https://laohu8.com/S/LENZ">Therapeutics</a> Announces Positive Results from Phase I/II Trial of Allocetra™ for Knee Osteoarthritis Treatment

Enlivex Therapeutics Ltd. has announced positive topline data from the Phase IIa stage of their clinical trial ENX-CL-05-001, which evaluates the efficacy of Allocetra™ in treating patients with moderate-to-severe knee osteoarthritis. The trial, a multi-center, two-stage Phase I/II double-blind, randomized, placebo-controlled study, demonstrated significant improvements in the treatment arm. In the modified intention-to-treat population, there was a 24% reduction in knee pain and a 26% improvement in knee function. Notably, in age-related primary osteoarthritis patients, a 72% reduction in knee pain and a 95% improvement in knee function were observed compared to placebo. The treatment also exhibited a favorable safety profile with no severe adverse events reported. The results were presented during a webinar held on August 18, 2025.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Enlivex Therapeutics Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9513803-en) on August 18, 2025, and is solely responsible for the information contained therein.

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