智通财经APP讯,绿竹生物-B(02480)发布公告,集团核心产品LZ901与重组糖蛋白E(gE)亚单位疫苗HZ/su疫苗(Shingrix®)进行头对头比较的一项随机、主动对照及非劣效性试验,在50岁及以上成人中获得了积极的免疫原性和安全性数据。该研究招募了301名50岁或以上健康成人,其中至少291名健康成人接种了两剂 LZ901或HZ/su疫苗。研究结果显示,与HZ/su疫苗相比,LZ901在50岁或以上成人中诱导出更优的细胞免疫原性和表现出更佳的安全性。
LZ901是集团自主开发的重组带状疱疹疫苗,并且是集团的核心产品,旨在预防年龄为40岁及以上成人带状疱疹及带状疱疹引致的相关并发症的发生(包括带状疱疹后遗神经痛)。截至本公告日期,LZ901的生物制品许可申请已获中华人民共和国国家药品监督管理局受理,目前正在评审中。
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