港股异动 | 东阳光药涨近7%,中期毛利14.68亿元,伊非尼酮关键数据亮相美国IPF峰会

智通财经
Sep 03

9月3日,东阳光药盘中涨近7%, 消息面上,近日,东阳光药发布2025年中期业绩,收入19.38亿元(人民币,下同);毛利14.68亿元。公告称,由于流感疫情相较去年同期有所放缓,集团磷酸奥司他韦产品作为流感首选用药受到一定影响,实现营业额13.01亿元,但依然保持行业的领先地位。

值得一提的是,第九届特发性肺纤维化(IPF)峰会于2025年8月19日至21日在美国波士顿召开。东阳光药亮相本次峰会,首席科学家林凯博士在大会主议程中首次公开披露在研抗纤维化创新药伊非尼酮(HEC585)的II期临床试验关键数据。

据介绍,此次峰会亮相的伊非尼酮是东阳光药自主研发的国产首个进入III期临床的IPF原研新药,同时可以拓展进行性纤维化性间质性肺疾病(PF-ILD)、乙肝肝纤维化、间质性肺炎等疾病。通过同时抑制TNF-α及TGF-β1的释放以及阻断TGF-β1-smad信号通路,从而抑制胶原等细胞外基质的沉积和纤维化进展,并通过NR4A1、BMP2等靶点调节PI3K-AKT、MAPK和Hippo信号通路,形成广泛的抗纤维化网络以达到治疗作用。

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