港股异动 | 歌礼制药-B(01672)早盘涨超5% ASC30注射剂半衰期长达75天 季度制剂成为可能

智通财经
Sep 10

智通财经APP获悉,歌礼制药-B(01672)早盘涨超5%,截至发稿,涨5.02%,报14.86港元,成交额2036.04万港元。

消息面上,歌礼制药宣布,小分子GLP-1受体(GLP-1R)激动剂ASC30用于减重维持的超长效皮下储库型(depot)制剂在美国Ib期临床研究的肥胖受试者中显示出75天的表观半衰期,该数据支持ASC30作为长期体重管理的维持疗法,每季度给药一次。ASC30减重维持制剂利用歌礼超长效药物开发平台开发而成。

东吴证券指出,公司下半年催化剂较多,多个重要临床数据即将披露:根据临床试验进度和公司公告,预计2025年Q4将读出ASC30口服II期、ASC47的I期及ASC50的I期顶线数据,2026年Q1将读出ASC30皮下注射II期顶线数据。同时公司预计未来6-9个月将向FDA申报2-3个新管线的IND,包含双靶点多肽减重管线。

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