A Look at Amicus Therapeutics's Valuation After New 4-Year PROPEL Study Results

Simply Wall St.

Sep 14

If you’ve been watching Amicus Therapeutics (FOLD) lately, you probably noticed the buzz after their recent data release. The company just unveiled fresh 4-year efficacy and safety results from its ...

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The company just unveiled fresh 4-year efficacy and safety results from its ...</p>\n\n<a href=\"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-fold/amicus-therapeutics/news/a-look-at-amicus-therapeuticss-valuation-after-new-4-year-pr\">Source Link</a>\n\n</div>\n","source":"simplywall_highlight","html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>A Look at Amicus Therapeutics's Valuation After New 4-Year PROPEL Study Results</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nA Look at Amicus Therapeutics's Valuation After New 4-Year PROPEL Study Results\n</h2>\n\n<h4 class=\"meta\">\n\n\n2025-09-14 02:23 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-fold/amicus-therapeutics/news/a-look-at-amicus-therapeuticss-valuation-after-new-4-year-pr><strong>Simply Wall St.</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>If you’ve been watching Amicus Therapeutics (FOLD) lately, you probably noticed the buzz after their recent data release. The company just unveiled fresh 4-year efficacy and safety results from its ...</p>\n\n<a href=\"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-fold/amicus-therapeutics/news/a-look-at-amicus-therapeuticss-valuation-after-new-4-year-pr\">Source Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"LU2065169927.USD","symbol_name":"M&G (LUX) GLOBAL MAXIMA \"A\" (USD) ACC","start_time":0,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-fold/amicus-therapeutics/news/a-look-at-amicus-therapeuticss-valuation-after-new-4-year-pr","article_id":"2567136323","we_media_id":null,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-fold/amicus-therapeutics/news/a-look-at-amicus-therapeuticss-valuation-after-new-4-year-pr","rn_cache_url":null,"directOrigin":true},"url":"https://stock-news.laohu8.com/highlight/detail?id=2567136323","pubTimestamp":1757787786,"columns":[],"sourceInfo":{"source_id":"simplywall_highlight","name":"Simply Wall St."},"weMediaInfo":null,"summary":"If you’ve been watching Amicus Therapeutics (FOLD) lately, you probably noticed the buzz after their recent data release. The company just unveiled fresh 4-year efficacy and safety results from its PROPEL open-label extension study, focused on cipaglucosidase alfa-atga plus miglustat for adults dealing with late-onset Pompe disease. Presented at a major medical conference, these updated findings offer a longer-term look at muscle function and patient outcomes, putting Amicus back on the radar...","collect":0,"end_time":0,"defaultTopTitle":"simplywall.st","property":[],"viewcount":null,"language":"en","relate_stocks":{"LU2065169927.USD":"M&G (LUX) GLOBAL MAXIMA \"A\" (USD) ACC","LU2065171402.SGD":"M&G (LUX) GLOBAL MAXIMA \"A\" (SGD) INC","DCF":"Dreyfus Alcentra Global Credit Income 2024 Target Term Fund, Inc","BK4139":"生物科技","LU2065170008.USD":"M&G (LUX) GLOBAL MAXIMA \"A\" (USD) INC","LU2065171311.SGD":"M&G (LUX) GLOBAL MAXIMA \"A\" (SGD) ACC","FOLD":"爱美医疗"},"translate_title":"新的4年PROPEL研究结果显示Amicus Therapeutics的估值","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"DCF":1,"FOLD":1},"content_text":"If you’ve been watching Amicus Therapeutics (FOLD) lately, you probably noticed the buzz after their recent data release. The company just unveiled fresh 4-year efficacy and safety results from its PROPEL open-label extension study, focused on cipaglucosidase alfa-atga plus miglustat for adults dealing with late-onset Pompe disease. Presented at a major medical conference, these updated findings offer a longer-term look at muscle function and patient outcomes, putting Amicus back on the radar for anyone tracking biotech opportunities. This update feeds into a bigger story that’s been developing over the past year. While Amicus shares have slipped about 29% in that time, the past month paints a different picture: the stock is up 11%, and momentum has been even stronger over the last 3 months, showing a solid 33% increase. That kind of shift suggests renewed optimism, possibly driven by the clinical progress and how it might shape future revenue streams or risk perceptions. The question now is whether the recent climb reflects true upside potential, or if the market has already priced in the growth story from these new results. Is there still room to run, or has the window for opportunity started to close? AdvertisementMost Popular Narrative: 50.3% Undervalued According to the most widely followed narrative, Amicus Therapeutics currently trades well below what analysts consider to be its fair value. The consensus points to significant upside potential if key growth assumptions hold true.  Expanding patient identification and improving diagnostic pathways have revealed a much larger underdiagnosed and untreated population for Fabry and Pompe diseases than previously estimated. This positions Amicus to drive sustained long-term revenue growth through increased patient penetration and global market expansion.  Curious which powerful trends could double the stock’s value? This narrative hinges on accelerated growth, wider margins, and bold profit milestones that could leave competitors scrambling. Wondering how these projections stack up against the current share price? Keep reading to uncover the full story fueling this dramatic undervaluation call. Result: Fair Value of $16.09 (UNDERVALUED) Have a read of the narrative in full and understand what's behind the forecasts. However, persistent net losses and reliance on just a few products mean that any misstep or competitive shift could quickly upend these bullish projections. Find out about the key risks to this Amicus Therapeutics narrative. Another View: What Does the SWS DCF Model Say? Looking at things from a different angle, our DCF model also points to Amicus being undervalued at present. This approach digs deeper into future cash flows rather than focusing on current sales. Could the true value be even further out of reach? Look into how the SWS DCF model arrives at its fair value. FOLD Discounted Cash Flow as at Sep 2025 Simply Wall St performs a discounted cash flow (DCF) on every stock in the world every day (check out Amicus Therapeutics for example). We show the entire calculation in full. You can track the result in your watchlist or portfolio and be alerted when this changes, or use our stock screener to discover undervalued stocks based on their cash flows. If you save a screener we even alert you when new companies match - so you never miss a potential opportunity.\n Build Your Own Amicus Therapeutics Narrative If you have your own perspective or want to put the numbers to the test yourself, it only takes a few minutes to craft your own view. So why not Do it your way? A good starting point is our analysis highlighting 4 key rewards investors are optimistic about regarding Amicus Therapeutics. Looking for more investment ideas? Don’t let the momentum stop here. With so many smart opportunities emerging in every sector, the next big win might be just one search away. Put yourself ahead of the crowd by checking out these tailored stock ideas designed for ambitious investors:  Capitalize on tomorrow’s breakthroughs by previewing rising stars powered by artificial intelligence with our AI penny stocks. Secure lasting income streams by reviewing companies offering yields over 3% through our selection of dividend stocks with yields > 3%. Catch undervalued gems before the broader market sees their potential by using our tool for undervalued stocks based on cash flows.   This article by Simply Wall St is general in nature. We provide commentary based on historical data\n    and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your\n    financial situation. We aim to bring you long-term focused analysis driven by fundamental data.\n    Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material.\n    Simply Wall St has no position in any stocks mentioned.New: Manage All Your Stock Portfolios in One PlaceWe've created the ultimate portfolio companion for stock investors, and it's free.• Connect an unlimited number of Portfolios and see your total in one currency• Be alerted to new Warning Signs or Risks via email or mobile• Track the Fair Value of your stocksTry a Demo Portfolio for FreeHave feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team@simplywallst.com","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"dataReport","news_rank":0,"symbols":[],"gpt_button":0,"need_auth":false,"code":"91000000","status":"200"}}}