Moderna Says Second Covid-19 Vaccine Generates Strong Immune Response

Dow Jones
Sep 23
 

By Nicholas G. Miller

 

Moderna said its updated mNexspike Covid-19 vaccine demonstrated a strong immune response against the dominant LP.8.1 variant, after previously saying its other Covid-19 vaccine, Spikevax, also demonstrated a strong immune response.

Data from an ongoing Phase 4 trial showed mNexspike produced a 16-fold increase in antibodies neutralizing LP.8.1. It said earlier this month that Spikevax generated an eight-fold increase in antibodies.

The 2025-2026 formula of mNexspike is approved for individuals 12 through 64 years of age with at least one underlying condition putting them at a high risk for severe outcomes from Covid-19 and all adults 65 years of age and older.

 

Write to Nicholas G. Miller at nicholas.miller@wsj.com.

 

(END) Dow Jones Newswires

September 23, 2025 07:27 ET (11:27 GMT)

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