产品用于轻中度特应性皮炎的中国三期临床研究成功达到主要终点,即使用芦可替尼乳膏治疗8周,达到研究者整体评估(IGA)评分为0或1分,且较基线改善≥2分的受试者比例,显著高于安慰剂(63.0% vs 9.2%,P<0.001)。关键次要终点,芦可替尼乳膏治疗8周达到湿疹面积及严重程度指数评分较基线至少改善75%(EASI 75)的受试者比例亦显著优于安慰剂(78.0% vs 15.4%,P<0.001)。安全性方面,治疗期出现的不良事件(TEAE)的严重程度大多数为轻度或中度,未发生导致研究药物用药终止的治疗期出现的不良事件(TEAE),整体安全耐受性良好。
此外,集团正积极推进产品在中国的新药上市申请(NDA)工作。
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