BUZZ-肺病药物未能达到试验目标,Tvardi Therapeutics跌停

路透中文
Yesterday
BUZZ-肺病药物未能达到试验目标,Tvardi <a href="https://laohu8.com/S/LENZ">Therapeutics</a>跌停

10月13日 - ** 药物开发商Tvardi Therapeutics TVRD.O股价盘前下跌88.6%至4.73美元

** 公司称其试验性药物TTI-101在特发性肺纤维化(一种慢性进行性肺病)患者的中期试验中未能达到预期目标

** 该试验对 88 名患者进行了 TTI-101 作为独立疗法或与德国勃林格殷格翰公司的宁替尼(nintedanib)联合疗法的评估

** Nintedanib已获得FDA批准,用于减缓IPF和其他肺部疾病患者的肺功能衰退。

** 试验中治疗组的停药率很高,400 毫克剂量为 56.7%,800 毫克剂量为 62.1%,而安慰剂的停药率为 10.3

** 大多数停药是由于胃肠道副作用,尤其是同时接受宁替达尼治疗的患者--TVRD

** 公司补充说,早期结果显示,该药对肺功能的改善与安慰剂相似

** 截至上一交易日收盘,该公司股价已上涨一倍多

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