Corcept Therapeutics Reports Positive Phase 3 Results for Relacorilant in Platinum-Resistant Ovarian Cancer
Reuters
Oct 19, 2025
Corcept Therapeutics Reports Positive Phase 3 Results for Relacorilant in Platinum-Resistant Ovarian Cancer
Corcept Therapeutics Incorporated has announced new data from its pivotal Phase 3 ROSELLA trial evaluating relacorilant in combination with nab-paclitaxel for patients with platinum-resistant ovarian cancer. The results, presented at the European Society for Medical Oncology (ESMO) 2025 Annual Meeting, demonstrated a progression-free survival benefit, particularly in patients whose disease progressed while on or after taking a PARP inhibitor. Additionally, Corcept reported the expansion of its Phase 2 BELLA trial to three study arms, which will examine the efficacy and safety of relacorilant plus nab-paclitaxel and bevacizumab in platinum-resistant and platinum-sensitive ovarian cancer, as well as relacorilant plus nab-paclitaxel in endometrial cancer. Initial results from the BELLA trial are expected in late 2026.
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