默沙东PD-1+ADC杀疯了

氨基观察
Oct 24, 2025

氨基观察-创新药组原创出品作者 | 沙晓微刚刚结束的ESMO大会上,默沙东的K药+ADC再度刷新治疗记录:在一项针对不适合或拒绝顺铂治疗的肌层浸润性膀胱癌(MIBC)患者的研究中,K药联合Nectin-4 ADC药物Padcev在新辅助、辅助治疗阶段均展现出显著临床获益:联合组较单纯手术组疾病复发、进展或死亡风险降低约60%,病理完全缓解率(pCR)高达57.1%(vs 8.6%)。至此,从晚期...

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