Nuvation Bio Highlights Breakthrough Oncology Advances and IBTROZI Launch in Corporate Presentation
Nuvation Bio Inc. has provided an update highlighting recent developments across its oncology portfolio. The company reported that IBTROZI™ (taletrectinib), a next-generation ROS1 inhibitor, received approval in the U.S., Japan, and China for advanced ROS1-positive non-small cell lung cancer (NSCLC), with 204 new patient starts in Q3 2025. Safusidenib, a brain-penetrant mIDH1 inhibitor, is entering a pivotal study for high-grade IDH1-mutant glioma, with plans to potentially include high-risk, low-grade patients. NUV-1511, a clinical-stage drug-drug conjugate, is in Phase 1/2 evaluation, while NUV-868, a BD2-selective BET inhibitor, has completed Phase 1 and Phase 1b studies. The company reported a cash balance of $549 million as of September 30, 2025, with additional funding available under a term loan agreement. You can access the full presentation through the link below.
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