OPKO Health (OPK) Is Down 9.3% After Regeneron Collaboration and Asset Sale Announcement – Has the Bull Case Changed?

Simply Wall St.

Nov 01

In the past week, OPKO Health announced a major research collaboration with Regeneron Pharmaceuticals to develop multispecific antibodies, while also reporting third-quarter earnings with revenue of ...

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These developments coincided with the completion of a significant asset sale and positive earnings surprise, highlighting a renewed operational focus and ability to secure high-value partnerships in the healthcare sector. We'll explore how OPKO Health's new Regeneron partnership and core business realignment may reshape its investment narrative going forward. Rare earth metals are an input to most high-tech devices, military and defence systems and electric vehicles. The global race is on to secure supply of these critical minerals. Beat the pack to uncover the 37 best rare earth metal stocks of the very few that mine this essential strategic resource.AdvertisementOPKO Health Investment Narrative RecapIf you are considering OPKO Health as an investment, the narrative centers on its ability to translate high-profile partnerships, like the new Regeneron collaboration, into consistent profitability and cash flow, which remains the key near-term catalyst. While the Regeneron agreement and recent asset sale reinforce OPKO’s focus on its core business, the most significant risk is still persistent unprofitability and reliance on transactional events over steady operating gains; the impact of this news on that risk appears limited for now. The recent sale of BioReference Health’s oncology assets to Labcorp is particularly relevant. This move streamlines OPKO’s diagnostics operations, reduces complexity, and is aligned with its aim to return the segment to profitability, a critical component for supporting future growth ambitions driven by milestone payments and broader partnerships. However, despite a renewed operational focus, investors should be aware that ongoing losses and dependence on external deals remain a concern if... Read the full narrative on OPKO Health (it's free!)OPKO Health's outlook projects $754.1 million in revenue and $40.6 million in earnings by 2028. This scenario assumes a 4.3% annual revenue growth and a $217.7 million increase in earnings from the current level of -$177.1 million.Uncover how OPKO Health's forecasts yield a $3.62 fair value, a 167% upside to its current price.Exploring Other PerspectivesOPK Community Fair Values as at Nov 2025 Fair value estimates from the Simply Wall St Community range widely, from US$1.85 to US$6.26, across three independent perspectives. As you compare these opinions, remember that the business is still unprofitable and relies heavily on key asset sales and partnerships for near-term progress, be sure to review a mix of forecasts before making your next decision.Explore 3 other fair value estimates on OPKO Health - why the stock might be worth over 4x more than the current price!Build Your Own OPKO Health NarrativeDisagree with existing narratives? Create your own in under 3 minutes - extraordinary investment returns rarely come from following the herd.A great starting point for your OPKO Health research is our analysis highlighting 1 key reward and 2 important warning signs that could impact your investment decision.Our free OPKO Health research report provides a comprehensive fundamental analysis summarized in a single visual - the Snowflake - making it easy to evaluate OPKO Health's overall financial health at a glance.Interested In Other Possibilities?Opportunities like this don't last. These are today's most promising picks. Check them out now:Find companies with promising cash flow potential yet trading below their fair value.We've found 22 US stocks that are forecast to pay a dividend yield of over 6% next year. See the full list for free.Uncover the next big thing with financially sound penny stocks that balance risk and reward.  This article by Simply Wall St is general in nature. We provide commentary based on historical data\n    and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your\n    financial situation. We aim to bring you long-term focused analysis driven by fundamental data.\n    Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material.\n    Simply Wall St has no position in any stocks mentioned.New: AI Stock Screener & AlertsOur new AI Stock Screener scans the market every day to uncover opportunities.• Dividend Powerhouses (3%+ Yield)• Undervalued Small Caps with Insider Buying• High growth Tech and AI CompaniesOr build your own from over 50 metrics.Explore Now for FreeHave feedback on this article? Concerned about the content? Get in touch with us directly. 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