AN2 Therapeutics Advances Chagas Disease and Oncology Programs and Reports Third Quarter 2025 Results
Reuters
Nov 13
AN2 Therapeutics Advances Chagas Disease and Oncology Programs and Reports Third Quarter 2025 Results
AN2 Therapeutics Inc. announced its third quarter 2025 financial results and recent business and scientific highlights. The company reported ongoing progress in its clinical pipeline, including the advancement of a Phase 1 first-in-human clinical trial for oral AN2-502998 targeting Chagas disease, with planning underway for a subsequent Phase 2 proof-of-concept study in collaboration with the Drugs for Neglected Diseases initiative (DNDi). The clinical-stage M. abscessus program is advancing through an investigator-initiated trial. In oncology, AN2 expects its first of two boron-based oncology targets to enter development in early 2026, with both programs aimed at solid-tumor cancers. AN2 also announced a research collaboration with GSK to develop boron-based LeuRS-inhibitors for tuberculosis (TB) and received a third year of funding from the Gates Foundation to support this work.
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