据21财经，近日，默沙东与Cidara Therapeutics共同宣布，双方已签署最终协议，根据该协议，默沙东将以约92亿美元的总额收购Cidara。这一消息发布后，位于圣地亚哥的生物技术公司Cidara的股价应声飙升超105%，创下2017年以来的最高水平。而这笔交易的核心筹码是Cidara的核心候选药物CD388，这是一种基于创新Drug-Fc Conjugate（DFC）技术平台的长效抗病毒药物，用于流感预防。根据公开信息，在传统流感疫苗平均预防效力仅为40%左右的背景下，CD388在2b期临床试验中最高剂量展现出76%的预防效力，且单次用药可提供长达4～5个月的保护。“若CD388成功获批上市，其展现出的76%预防效力远高于传统疫苗，有望打开百亿美元级市场。结合默沙东成熟的商业化网络与全球渠道，协同效应下净现值（NPV）或远超收购成本。默沙东近年持续加码传染病领域布局（如新冠药物Lagevrio、HPV疫苗Gardasil等），此次收购其希望通过引入Cidara的专有Cloudbreak平台技术，进一步强化在‘免疫激活型抗感染药物’领域的管线厚度，为中长期增长储备新引擎。”有券商医药行业分析师对记者表示。
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