Opthea Limited has announced that the voluntary delisting of its American Depositary Shares (ADSs) from the Nasdaq Global Select Market became effective on November 21, 2025. Following the delisting, Opthea will file a Form 15F to deregister and terminate its reporting obligations in the United States, with deregistration expected to become effective 90 days after the filing. The company's ordinary shares will continue to be listed and primarily traded on the Australian Securities Exchange $(ASX)$, although trading remains suspended under ASX Listing Rule 17.3. After leaving Nasdaq, Opthea's ADSs may still be traded through the U.S. Over-The-Counter (OTC) market.
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