Imugene and JW Therapeutics Partner to Advance CAR-T and Oncolytic Virus Therapy for Solid Tumors

Reuters
Nov 28
Imugene and JW <a href="https://laohu8.com/S/LENZ">Therapeutics</a> Partner to Advance CAR-T and Oncolytic Virus Therapy for Solid Tumors

Imugene Limited has announced a strategic collaboration with JW Therapeutics to advance a novel combination therapy for refractory solid tumors. The partnership will evaluate Imugene's onCARlytics (CF33-CD19) oncolytic virus in combination with JW Therapeutics' Carteyva®, an approved CD19-directed autologous CAR-T cell therapy. The initiative includes preclinical studies and a Phase 1 investigator-initiated trial in China, employing a "mark and kill" strategy where the oncolytic virus induces CD19 expression on tumor cells, making them targetable by CAR-T cells. The collaboration aims to generate impactful preclinical and clinical data to explore new treatment paradigms for solid tumors.

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