Lineage Cell Therapeutics Achieves Milestone in Collaboration with Genentech and Roche
Reuters
Nov 25, 2025
Lineage Cell Therapeutics Achieves Milestone in Collaboration with Genentech and Roche
Lineage Cell Therapeutics Inc. has entered into a worldwide collaboration with Roche and Genentech, a member of the Roche Group, for the development of OpRegen® (RG6501), a suspension of human allogeneic retinal pigment epithelial (RPE) cells aimed at treating geographic atrophy (GA) secondary to dry age-related macular degeneration $(AMD)$. Lineage recently announced the achievement of the first milestone under this collaboration, which is tied to manufacturing and clinical advancements in the OpRegen cell therapy program. The partnership includes potential milestone payments totaling up to $620 million and involves an exclusive global development effort currently being evaluated in a Phase 2a clinical study.
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