亚虹医药(688176.SH)在ECC发布APL-1401Ⅰb期临床试验相关数据

智通财经
Dec 03, 2025

智通财经APP讯,亚虹医药(688176.SH)发布公告,近日,公司开展的APL-1401用于治疗中重度活动性溃疡性结肠炎的Ⅰb期临床试验结果入选第19届欧洲结直肠大会(ECC),并以壁报形式发布该研究的临床数据。

APL-1401是公司通过自主研究并发现其全新作用机制用于治疗自身免疫疾病的口服创新药物。APL-1401是一种强效、选择性的多巴胺β-羟化酶(DBH)抑制剂,通过抑制DBH,从而阻断了多巴胺(DA)合成去甲肾上腺素(NE)唯一的催化酶,导致DA升高、NE降低,使肠道免疫稳态恢复正常。

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