FDA批准阿斯利康（AZN）与第一三共（Daiichi Sankyo，TYO：4568）的fam-trastuzumab deruxtecan（Enhertu）联合帕妥珠单抗（pertuzumab）用于一线治疗，因DESTINY-Breast09试验显示其中位无进展生存期（PFS）达40.7个月，优于标准THP方案的26.9个月；帕妥珠单抗由罗氏（SWX：ROG）销售。

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