Monte Rosa Therapeutics Showcases Pipeline Advances and Strategic Partnerships in Targeted Protein Degradation
Reuters
Yesterday
Monte Rosa Therapeutics Showcases Pipeline Advances and Strategic Partnerships in Targeted Protein Degradation
Monte Rosa Therapeutics Inc. highlighted progress in its pipeline of molecular glue degraders (MGDs), with three clinical programs advancing toward Phase 2 trials anticipated in 2026. The company is targeting highly validated proteins implicated in diseases with significant unmet medical needs, leveraging its AI-driven QuEEN platform for rational design and selectivity. Recent collaborations include a partnership with Novartis to accelerate development of degraders for immune-mediated diseases, featuring an upfront payment of $120 million and potential deal value up to $5.7 billion. Another agreement with Roche focuses on cancer and neurological disease targets, with Monte Rosa leading early-stage activities. The company anticipates additional investigational new drug applications for its pipeline over the next two years. You can access the full presentation through the link below.
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