Small U.S. Stocks Close Lower; Jyong Biotech Falls Furthest

Dow Jones
Dec 17, 2025

This article was automatically generated using Dow Jones technology.

Shares of small-cap companies declined Tuesday, as the Russell 2000 Index dropped 0.4%, and the S&P Small Cap 600 Index was down 0.7%.

Among companies with a market value of $1 billion to $6.7 billion, Jyong Biotech Ltd. was the biggest laggard during the session, dropping 31%, followed by shares of Frontier Group Holdings Inc., which dropped 11%. Shares of PBF Energy Inc. dropped 11%, Maase Inc. shares plunged 9.0%, and Expro Group Holdings N.V. plunged 8.2%.

Tilray Brands Inc. was the best performer, surging 28%, followed by Monte Rosa Therapeutics Inc., which surged 13%. Zenas BioPharma Inc. shares surged 13%, Polibeli Group Ltd. surged 12%, and shares of Sezzle Inc. jumped 10%.

Major stock indexes in the U.S. closed mixed Tuesday with the Nasdaq Composite Index increasing 0.2%. Meanwhile, the S&P 500 Index fell 0.2%, and the Dow Jones Industrial Average declined 0.6%.

Data source: Dow Jones Market Data, FactSet

 

(END) Dow Jones Newswires

December 16, 2025 16:21 ET (21:21 GMT)

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