Wall Street's main indexes were slightly higher in volatile trading on Wednesday as investors searched for clues on the outlook for interest rates, while caution lingered following reports of funding hurdles for Oracle's data center plans. .N

At 10:30 EST, the Dow Jones Industrial Average .DJI was up 0.36% at 48,286.10.The S&P 500 .SPX was down 0.03% at 6,797.17, and the Nasdaq Composite .IXIC was down 0.17% at 23,072.17.

The top three S&P 500 .PG.INX percentage gainers:

** Texas Pacific Land Corp , up 7.4%

** Albemarle Corp , up 5.2%

** Moderna Inc , up 4.9%

The top three S&P 500 .PL.INX percentage losers:

** Brown-Forman Corp , down 4.9%

** Oracle Corp , down 4.9%

** $Lennar Corp(LEN/WD)$ , down 4.6%

The top three NYSE .PG.N percentage gainers:

** Dingdong (Cayman) Ltd , up 17.3%

** Two Harbors Investment Corp , up 12.9%

** Ashford Hospitality Trust Inc , up 9.8%

The top three NYSE .PL.N percentage losers:

** Spire Global Inc , down 21.8%

** Gray Media Inc , down 8.5%

** Sos Ltd , down 7.3%

The top three Nasdaq .PG.O percentage gainers:

** Processa Pharmaceuticals Inc , up 169.9%

** Vyne Therapeutics Inc , up 73.6%

** Agape ATP Corp , up 49.9%

The top three Nasdaq .PL.O percentage losers:

** Vistagen Therapeutics Inc , down 82.7%

** Children's Place Inc , down 36.7%

** Vision Marine Technologies Inc , down 34.6%

** Netflix Inc NFLX.O:BUZZ - Rises as Warner Bros board leans toward buyout nL6N3XN0JR

** Hecla Mining Co HL.N:

** Coeur Mining Inc CDE.N:

** Endeavour Silver Corp EXK.N:

** Silvercorp Metals Inc SVM.N:

BUZZ - Silver miners gain as precious metal soars to new peak nL6N3XN11U

** Newmont Corp NEM.N:

** Agnico Eagle Mines Ltd AEM.N:

** Kinross Gold Corp KGC.N:

** Harmony Gold Mining Co Ltd HMY.N::

BUZZ - Gold miners gain as bullion rises on softening US labor market nL4N3XN19G

** Amazon.com Inc AMZN.O:BUZZ - Gains after source points to talks for $10 bln OpenAI investment nL6N3XN0LU

** Jabil Inc JBL.N:BUZZ - Seen reporting jump in rev, EPS in results Wed nL6N3XM15F

** Sociedad Química y Minera de Chile SQM.N:

** Sigma Lithium Corp SGML.O:

** Lithium Americas Corp LAC.N:

BUZZ - Lithium miners rise as prices surge after China revokes mining licenses nL4N3XN1C1

** Palo Alto Networks Inc PANW.O:BUZZ - Gains as JP Morgan resumes coverage with 'overweight' rating nL6N3XN0O4

** Rio Tinto PLC RIO.N:

** BHP Group Ltd BHP.N:

** Southern Copper Corp SCCO.N:

** Freeport-McMoRan Inc FCX.N:

BUZZ - Copper miners rise on supply worries despite mixed U.S. labor data nL6N3XN0NU

** FedEx Corp FDX.N:BUZZ - Deutsche Bank lifts FedEx's PT, sees profit boost from network revamp nL4N3XN0V5

** T1 Energy Inc TE.N:BUZZ - Gains as solar cell facility construction begins nL6N3XN0OH

** Kymera Therapeutics Inc KYMR.O:

** Apogee Therapeutics Inc APOG.O:

** Xenon Pharmaceuticals Inc XENE.O:

** Ascendis Pharma A/S ASND.O:BUZZ - RBC says biotech sector's rebound has momentum, with intriguing opportunities for 2026 nL6N3XN0QE

** AAR Corp AIR.N:BUZZ - Jefferies initiates coverage on AAR Corp with 'buy' rating nL4N3W414L

** Hut 8 Corp HUT.O:BUZZ - Jumps on $7 bln AI infrastructure deal with Anthropic nL6N3XN0P7

** Victoria's Secret & Co VSCO.N:BUZZ - Rises after Telsey Advisory Group upgrades stock to 'outperform' nL6N3XN0PR

** WesBanco Inc WSBC.O:

** First Commonwealth Financial Corp FCF.N:

** Financial Institutions Inc FISI.O:

** Northwest Bancshares Inc NWBI.O:BUZZ - Piper Sandler assumes coverage of five US Northeast banks nL4N3XN0V7

** Waters Inc WAT.N:

** Neogenomics Inc NEO.O:

** Avantor Inc AVTR.N:

** $Danaher Corp(DHR-W)$ DHR.N:BUZZ - Jefferies updates ratings on life sciences firms for 2026 nL4N3XN0WL

** McKesson Corp MCK.N:

** Cencora Inc COR.N:

** UnitedHealth Group Inc UNH.N:

** CVS Health Corp CVS.N:BUZZ - J.P.Morgan sees brighter outlook for US healthcare services in 2026 nL4N3XN0WE

** Fortinet Inc FTNT.O:BUZZ - Falls after JP Morgan downgrades to 'underweight' nL6N3XN0W4

** General Mills Inc GIS.N:BUZZ - Up after quarterly results beat estimates on steady demand nL6N3XN121

** Paramount Skydance Corp PSKY.O:BUZZ - Down after Warner Bros Discovery rejects co's bid nL4N3XN0ZF

** Nucor Corp NUE.N:

** Steel Dynamics Inc STLD.O:BUZZ - Falls amid weak Q4 earnings forecast nL6N3XN0Y1

** Veru Inc VERU.O:BUZZ - Rises after US FDA backs obesity drug combo plan nL6N3XN0XZ

**Jabil Inc JBL.N:BUZZ - Rises on upbeat annual results forecasts nL4N3XN192

** Immunome Inc IMNM.O:BUZZ - Slips after $400 mln stock sale nL6N3XN0XK

** Coursera Inc COUR.N:

** Udemy Inc UDMY.O:BUZZ - Gain as online learning providers ink about $930 million deal []nL6N3XN11X

** Texas Pacific Land Corp TPL.N:BUZZ - Rises on deal with Bolt Data & Energy nL6N3XN0X1

** Vor Biopharma Inc VOR.O:BUZZ - Jumps after TD Cowen initiates coverage with 'buy' nL6N3XN0OL

** Cytokinetics Inc CYTK.O:BUZZ - Rises after winning China approval for heart disease drug nL4N3XN12B

** Texas Roadhouse Inc TXRH.O:BUZZ - Up after Wells Fargo upgrades stock, hikes PT nL6N3XN0YG

** Oracle Corp ORCL.N:BUZZ - Down on report Blue Owl Capital will not back $10 billion deal for Michigan data center nL4N3XN145

** Kodiak Sciences Inc KOD.O:BUZZ - Surges after boosted $160 mln equity raise nL6N3XN12N

** ABM Industries Inc ABM.N:BUZZ - Rises after fourth-quarter revenue beats estimates nL4N3WG179

** Spotify Inc SPOT.N:BUZZ - Rises as Citizens initiates with 'market outperform' nL6N3XN10G

** Robinhood Markets Inc HOOD.O:BUZZ - Gets 'buy' rating as Truist starts coverage nL4N3XN11K

**Albemarle Corp ALB.N:BUZZ - Truist raises Albemarle PT on lithium market momentum; shares rise nL6N3XN0XF

** Exxon Mobil Corp XOM.N:

** Chevron Corp CVX.N:

** ConocoPhillips COP.N:

** EQT Corp EQT.N:

BUZZ - Energy firms gain as Trump's Venezuela blockade stokes uncertainty nL4N3XN16Y

** Plug Power Inc PLUG.O:BUZZ - Rises after installing electrolyzer for Namibia green hydrogen project nL6N3XN10E

** Kyverna Therapeutics Inc KYTX.O:BUZZ - Tumbles on deep-discounted $100 mln stock deal nL6N3XN10K

** New Fortress Energy Inc NFE.O:BUZZ - Extends forbearance agreement; shares rise nL3N3VG0JM

** Cronos Group Inc CRON.O:

** Aurora Cannabis Inc ACB.O:

** Tilray Brands Inc TLRY.O:

** Canopy Growth Corp CGC.O:BUZZ - Cannabis stocks rise on report saying Trump may ease curbs this week nL6N3XN12F

** CNX Resources Corp CNX.N:

** EQT Corp EQT.N:

** Cheniere Energy Inc LNG.N:

** Williams Companies Inc WMB.N:

BUZZ - US natgas companies gain on strong LNG export flows, higher demand nL4N3XN1CV

(Rajarshi Roy and Anshi Sancheti)

((Anshi.Sancheti@thomsonreuters.com))