Guangdong HEC Pharmaceutical Launches Phase I Trial of Novel Hepatitis B siRNA Drug

Reuters

Jan 05

Guangdong HEC Pharmaceutical Launches Phase I Trial of Novel Hepatitis B siRNA Drug

Guangdong HEC Pharmaceutical Co. Ltd. has announced the initiation of a Phase I clinical trial for HECN30227, an siRNA therapeutic targeting hepatitis B virus. HECN30227 is a Class 1 new drug independently developed by the company, with global intellectual property rights. Preclinical data indicate that HECN30227 demonstrates pan-genotypic activity and is effective in reducing hepatitis B surface antigen (HBsAg) levels, including efficacy against strains resistant to nucleoside analogues. The company has not yet presented clinical results, as the announcement pertains to the commencement of the Phase I trial.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Guangdong HEC Pharmaceutical Co. Ltd. published the original content used to generate this news brief via IIS, the Issuer Information Service operated by the Hong Kong Stock Exchange (HKex) (Ref. ID: HKEX-EPS-20260105-11979976), on January 05, 2026, and is solely responsible for the information contained therein.

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Ltd. published the original content used to generate th","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"BK1191":"制药","06887":"东阳光药"},"translate_title":"广东东阳光药启动乙肝siRNA新药I期试验","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"06887":0.9},"content_text":"Guangdong HEC Pharmaceutical Launches Phase I Trial of Novel Hepatitis B siRNA Drug\n    \n\n        Guangdong HEC Pharmaceutical Co. Ltd. has announced the initiation of a Phase I clinical trial for HECN30227, an siRNA therapeutic targeting hepatitis B virus. HECN30227 is a Class 1 new drug independently developed by the company, with global intellectual property rights. Preclinical data indicate that HECN30227 demonstrates pan-genotypic activity and is effective in reducing hepatitis B surface antigen (HBsAg) levels, including efficacy against strains resistant to nucleoside analogues. 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