Alto Neuroscience Inc. announced the issuance of U.S. Patent Number 12,521,374 covering methods of treating depression with ALTO-207, a novel combination of pramipexole and ondansetron. The patent protects the use of ondansetron to mitigate pramipexole-related side effects, enabling patients to achieve higher doses needed for antidepressant benefits. The company expects its issued and pending claims to protect ALTO-207 into the mid-2040s, strengthening the intellectual property position of this investigational therapy for treatment-resistant depression.
Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Alto Neuroscience Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20260114749833) on January 14, 2026, and is solely responsible for the information contained therein.