Major US equity indexes closed lower Tuesday as investors weighed bank earnings and December inflation data.

* The consumer price index rose 2.7% in December from a year earlier, matching November's annual increase and meeting expectations. Core CPI, which excludes food and energy costs, rose 2.6% in December from a year earlier, below the expected 2.7% gain.

* February West Texas Intermediate crude oil rose $1.49 to settle at $60.99 per barrel, while March Brent crude, the global benchmark, was last seen up $1.48 at $65.35.

JPMorgan Chase (JPM) reported Q4 adjusted earnings above market expectations, though revenue fell short of estimates amid lower investment-banking fees. CEO Jamie Dimon said markets are underappreciating macroeconomic headwinds despite the US economy remaining "resilient." The shares fell 4.2%.

* Moderna (MRNA) shares rose 17% after the company said it expects 2025 revenue to come in close to the top its guidance range, while the drugmaker affirmed its revenue outlook for this year.

* Adobe (ADBE) shares fell 5.4% after Oppenheimer downgraded the stock to market perform from outperform.