港股异动 | 映恩生物-B(09606)早盘涨超4% ADAM9靶向ADC癌症新药在中国获批临床

智通财经
Jan 20

智通财经APP获悉,映恩生物-B(09606)早盘涨超4%,截至发稿,涨2.42%,报363.6港元,成交额5105.75万港元。

消息面上,1月19日,映恩生物宣布,公司自主研发的ADAM9靶向抗体偶联药物(ADC)DB-1317已获得国家药监局药品审评中心(CDE)的新药临床试验批准,同意其单药在晚期/转移性恶性实体瘤患者中开展临床试验。

据悉,DB-1317是映恩生物基于公司自主研发的ADC技术平台DITAC开发的新一代ADC产品,具有全球权益。其靶点ADAM9在胃癌、结直肠癌、胰腺癌、非小细胞肺癌等多种肿瘤中高表达,而在正常组织中表达水平较低。临床前研究显示,DB-1317在多种肿瘤模型中表现出显著的抗肿瘤活性。

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