Boundless Bio Inc. has released a corporate presentation detailing its latest developments in cancer treatment targeting oncogene amplified cancers, which represent a significant unmet medical need with approximately 1.3 million new patients annually in major markets. The company highlights its focus on therapies directed at extrachromosomal DNA (ecDNA), a cancer-specific circular DNA implicated in oncogene amplification. Boundless Bio's drug discovery platform, Spyglass, is used to identify synthetic lethal targets in these cancers. The company’s pipeline includes BBI-940, an oral Kinesin degrader with an accepted IND and a clinical trial set to begin in the first half of 2026. In addition, four other ecDNA-selective targets are under development, with one at the hit-to-lead stage. Boundless Bio reports a cash runway expected to last into the second half of 2028, supporting continued research and development activities. You can access the full presentation through the link below.
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