智通财经APP讯，先声药业(02096)发布公告，于2026年1月26日，集团附属公司先声药业有限公司(江苏先声)与勃林格殷格翰签署独家授权许可协议。根据该协议条款，勃林格殷格翰将获得用于炎症性肠病的TL1A/IL-23p19双特异性抗体SIM0709在大中华区以外的全球独家权益。本次授权许可进一步验证了集团自身免疫研发平台的创新性及领先性。
根据该协议条款，集团有权收取4200万欧元的首付款，以及基于研发进展、监管审批及商业化等情况，最高达10.16亿欧元的里程碑付款。此外，集团亦有权就大中华区以外的净销售额收取分级特许权使用费。
SIM0709为集团基于自有多特异性抗体平台自主研发的长效人源化双特异性抗体。SIM0709可同时靶向肿瘤坏死因子配体超家族成员15(TL1A)和白介素-23(IL-23)，从而阻断参与炎症性肠病发生及进展的两条核心通路。SIM0709在体外原代细胞实验和体内动物实验中均表现出优异的药效协同效果，甚至优于两个单药的联用。
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