和铂医药全人源抗体技术平台:助力开发高危禽流感H5N1中和抗体

医药笔记
Jan 28

▎Armstrong2025年12月,西奈山医学院科学家在Nature Communications期刊上发表了一篇重要研究文章,团队筛选出针对高致病性流感H5N1病毒(2.3.4.4b分支)血凝素(HA)的全人源中和抗体,一些中和抗体在小鼠体内攻毒实验中表现出优异的预防和治疗效果,最低0.1mg/kg剂量即可实现完全保护。2020年以来,2.3.4.4b分支H5N1病毒在全球野生鸟类中广泛传播,...

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