Edding Genor Group Doses First Patient in Phase II Trial of EDP167 for HoFH

Reuters
Feb 09
Edding Genor Group Doses First Patient in Phase II Trial of EDP167 for HoFH

Edding Genor Group Holdings Limited has announced the completion of the first subject dosing in a Phase II clinical trial of its innovative small nucleic acid drug, EDP167. The Phase II trial is a multicenter, dose-finding, and open-label study evaluating the efficacy and safety of EDP167 in adult patients with Homozygous Familial Hypercholesterolemia (HoFH). The primary endpoint is the change in low-density lipoprotein cholesterol (LDL-C) levels relative to baseline after 24 weeks of treatment. Previous Phase I studies in healthy subjects and individuals with mild dyslipidemia indicated that EDP167 demonstrated a favorable safety and tolerability profile. The results of these studies are scheduled to be disclosed at a medical conference in 2026.

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