BUZZ-Evommune soars after eczema therapy shows promise in mid-stage trial

Reuters
Feb 10
BUZZ-<a href="https://laohu8.com/S/EVMN">Evommune</a> soars after eczema therapy shows promise in mid-stage trial

** Shares of drug developer Evommune EVMN.N jump 102.47% to $33.8 premarket

** Co says its experimental therapy, EVO301, met the main goal of a mid-stage trial, when tested in patients with moderate-to-severe atopic dermatitis

** Atopic dermatitis, or eczema, is a chronic skin condition causing dry, itchy, inflamed skin due to a faulty skin barrier and overactive immune response

** In a 70-patient trial, 23% of patients on EVO301 had clear or almost clear skin with a meaningful improvement, compared with patients on placebo

** EVO301 is an injectable protein drug designed to block IL‑18, an inflammatory signal that is overactive in conditions like atopic dermatitis

** Patients on co's therapy showed statistically significant reduction in their EASI scores - a standard measure of eczema severity - compared with people who received placebo by week 4, 8 and 12 of the study

** EVMN says it is also evaluating potential additional indications for EVO301, including ulcerative colitis

** Up to last close, stock has been down 16% in last 12 months

(Reporting by Siddhi Mahatole)

((siddhi.mahatole@thomsonreuters.com))

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