.

** Shares of InSilico Medicine Cayman TopCo 3696.HK jump 9.9% to HK$73.8, a fresh high since their debut on December 30, 2025

** Stock on track for biggest daily gain since February 3; on track for second session of rise

** InSilico says it has entered into a strategic partnership with China Medical System 0867.HK on innovative drug development in the fields of central nervous system and autoimmune diseases

** Insilico says the two parties will jointly advance the co-development of no fewer than two R&D programs

** The company is expected to receive R&D funding support of up to several tens of millions of Hong Kong dollars for each program

** Shares of China Medical System slip 2%

** Insilico stock has soared 202% from the HK$24.05 IPO price in nearly 6 weeks

** YTD, Insilico shares up 92.5%, Hang Seng Biotech Index .HSBIO up 11.3%

(Reporting by Donny Kwok)

((donny.kwok@thomsonreuters.com))