智通财经APP获悉，周一，礼来(LLY.US)涨逾3%，报1095.87美元。消息面上，2月9日，Orna Therapeutics宣布与礼来达成最终收购协议，礼来将全面收购Orna，以强化其在细胞疗法与基因药物领域的布局。Orna股东最高可获得24亿美元现金，包括预付款及达成特定临床开发里程碑后的后续款项。
根据协议，本次收购的核心标的是Orna的环状RNA技术平台及体内CAR-T管线。Orna深耕工程化环状RNA与新型脂质纳米粒(LNP)递送系统结合的创新疗法，可让患者自身机体生成治疗性细胞，直击疾病根源，其技术优势在于能实现治疗蛋白更持久的表达，突破当前RNA及细胞疗法的局限。
据悉，Orna的核心项目ORN-252是一款已具备临床申报条件、靶向CD19的体内CAR-T疗法，主要用于治疗B细胞介导的自身免疫性疾病，这也是礼来重点关注的领域。
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