Karyopharm Therapeutics Showcases Pipeline Advances and Upcoming Phase 3 Data in Cancer Therapies

Reuters

Feb 12

Karyopharm <a href="https://laohu8.com/S/LENZ">Therapeutics</a> Showcases Pipeline Advances and Upcoming Phase 3 Data in Cancer Therapies

Karyopharm Therapeutics Inc. has released a corporate presentation outlining key developments for 2026. The presentation highlights the company's lead asset, XPOVIO® (selinexor), which is now approved in over 50 countries and is being evaluated for additional indications. Top-line data from two Phase 3 trials are anticipated in 2026: the SENTRY trial of selinexor plus ruxolitinib in myelofibrosis, with results expected in March, and the XPORT-EC-042 trial of selinexor in endometrial cancer, with results expected mid-year. Karyopharm projects that selinexor could reach a peak annual revenue opportunity of up to approximately $1 billion in myelofibrosis, pending positive trial results and regulatory approval. The company also notes its existing commercial infrastructure in the U.S., which is positioned to support future product launches. You can access the full presentation through the link below.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Karyopharm Therapeutics Inc. published the original content used to generate this news brief on February 12, 2026, and is solely responsible for the information contained therein.

Disclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.

Most Discussed

1
2
3
4
5
6
7
8
9
10

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers | Global Stocks, Options & Futures Trading App","description":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","keywords":"tiger brokers,tiger trade,tiger brokers singapore,broker online,stock trading in singapore,share trading singapore,brokerage firm singapore,trading app,stock broker singapore,stock trading platforms,trading account","social":{"ogDescription":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.be62fbe1.png","ogUrl":"https://www.itiger.com/news/2610924574"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental"},"isCrawlerRequest":true,"__swrFallback__":{"@#url:\"https://stock-news.skytigris.cn/v3/news\",params:#id:\"2610924574\",edition:\"fundamental\",auth_exemption:1,,,undefined,":{"share":"https://ttm.financial/m/news/2610924574?lang=en_US&edition=fundamental","thumbnail":"","is_english":true,"pubTime":"2026-02-12 21:53","share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","id":"2610924574","market":"us","top_or_hot":-1,"title":"Karyopharm Therapeutics Showcases Pipeline Advances and Upcoming Phase 3 Data in Cancer Therapies","media":"Reuters","content":"<html xmlns=\"http://www.w3.org/1999/xhtml\" xmlns:newsg2=\"http://iptc.org/std/nar/2006-10-01/\" xmlns:xhtml=\"http://www.w3.org/1999/xhtml\"><head><title>\n      Karyopharm <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> Showcases Pipeline Advances and Upcoming Phase 3 Data in Cancer Therapies\n    </title></head><body><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n        <a href=\"https://laohu8.com/S/KPTI\">Karyopharm Therapeutics Inc.</a> has released a corporate presentation outlining key developments for 2026. The presentation highlights the company's lead asset, XPOVIO® (selinexor), which is now approved in over 50 countries and is being evaluated for additional indications. Top-line data from two Phase 3 trials are anticipated in 2026: the SENTRY trial of selinexor plus ruxolitinib in myelofibrosis, with results expected in March, and the XPORT-EC-042 trial of selinexor in endometrial cancer, with results expected mid-year. Karyopharm projects that selinexor could reach a peak annual revenue opportunity of up to approximately $1 billion in myelofibrosis, pending positive trial results and regulatory approval. The company also notes its existing commercial infrastructure in the U.S., which is positioned to support future product launches. You can access the full presentation through the link below.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n<i>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Karyopharm Therapeutics Inc. published the original content used to generate this news brief on February 12, 2026, and is solely responsible for the information contained therein.</span></i>\n</p>\n</div></body></html>","source":null,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Karyopharm Therapeutics Showcases Pipeline Advances and Upcoming Phase 3 Data in Cancer Therapies</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nKaryopharm Therapeutics Showcases Pipeline Advances and Upcoming Phase 3 Data in Cancer Therapies\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1032215980\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Reuters </p>\n<p class=\"h-time\">2026-02-12 21:53</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<html xmlns=\"http://www.w3.org/1999/xhtml\" xmlns:newsg2=\"http://iptc.org/std/nar/2006-10-01/\" xmlns:xhtml=\"http://www.w3.org/1999/xhtml\"><head><title>\n      Karyopharm <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> Showcases Pipeline Advances and Upcoming Phase 3 Data in Cancer Therapies\n    </title></head><body><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n        <a href=\"https://laohu8.com/S/KPTI\">Karyopharm Therapeutics Inc.</a> has released a corporate presentation outlining key developments for 2026. The presentation highlights the company's lead asset, XPOVIO® (selinexor), which is now approved in over 50 countries and is being evaluated for additional indications. Top-line data from two Phase 3 trials are anticipated in 2026: the SENTRY trial of selinexor plus ruxolitinib in myelofibrosis, with results expected in March, and the XPORT-EC-042 trial of selinexor in endometrial cancer, with results expected mid-year. Karyopharm projects that selinexor could reach a peak annual revenue opportunity of up to approximately $1 billion in myelofibrosis, pending positive trial results and regulatory approval. The company also notes its existing commercial infrastructure in the U.S., which is positioned to support future product launches. You can access the full presentation through the link below.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n<i>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Karyopharm Therapeutics Inc. published the original content used to generate this news brief on February 12, 2026, and is solely responsible for the information contained therein.</span></i>\n</p>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4139","symbol_name":"生物科技","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260212:nNDL1WBrKR:1","article_id":"2610924574","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2610924574","pubTimestamp":1770904423,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Karyopharm Therapeutics Inc. has released a corporate presentation outlining key developments for 2026. The presentation highlights the company's lead asset, XPOVIO , which is now approved in over 50 countries and is being evaluated for additional indications. Top-line data from two Phase 3 trials are anticipated in 2026: the SENTRY trial of selinexor plus ruxolitinib in myelofibrosis, with results expected in March, and the XPORT-EC-042 trial of selinexor in endometrial cancer, with results expected mid-year. Karyopharm projects that selinexor could reach a peak annual revenue opportunity of up to approximately $1 billion in myelofibrosis, pending positive trial results and regulatory approval. The company also notes its existing commercial infrastructure in the U.S., which is positioned to support future product launches. You can access the full presentation through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"BK4139":"生物科技","KPTI":"Karyopharm Therapeutics Inc."},"translate_title":"Karyopharm Therapeutics展示了癌症疗法的管道进展和即将推出的3期数据","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"KPTI":0.9},"content_text":"Karyopharm Therapeutics Showcases Pipeline Advances and Upcoming Phase 3 Data in Cancer Therapies\n    \n\nKaryopharm Therapeutics Inc. has released a corporate presentation outlining key developments for 2026. The presentation highlights the company's lead asset, XPOVIO® (selinexor), which is now approved in over 50 countries and is being evaluated for additional indications. Top-line data from two Phase 3 trials are anticipated in 2026: the SENTRY trial of selinexor plus ruxolitinib in myelofibrosis, with results expected in March, and the XPORT-EC-042 trial of selinexor in endometrial cancer, with results expected mid-year. Karyopharm projects that selinexor could reach a peak annual revenue opportunity of up to approximately $1 billion in myelofibrosis, pending positive trial results and regulatory approval. The company also notes its existing commercial infrastructure in the U.S., which is positioned to support future product launches. You can access the full presentation through the link below.\n      \n\n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Karyopharm Therapeutics Inc. published the original content used to generate this news brief on February 12, 2026, and is solely responsible for the information contained therein.","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"productRelease","news_rank":0,"symbols":[],"gpt_button":0,"need_auth":false,"code":"91000000","status":"200"}}}