港股异动 | 中国抗体-B(03681)再涨超5% SM17临床前研究凸显治疗CRSwNP和IPF强大潜力

智通财经
Feb 20

智通财经APP获悉,中国抗体-B(03681)再涨超5%,截至发稿,涨4.62%,报2.04港元,成交额1336.18万港元。

消息面上,中国抗体宣布,其同类首创抗IL-17RB抗体SM17的临床前研究已在《欧洲呼吸杂志子刊-开放研究》上发表。该研究显示,SM17通过双重抑制Th2/Th17通路及抗纤维化活性,显著改善慢性鼻窦炎伴鼻息肉(CRSwNP)和特发性肺纤维化(IPF)的病理特征,支持其成为变革性疗法的潜力。

中国抗体董事长、执行董事兼首席执行官梁瑞安称,非常高兴公司在《欧洲呼吸杂志子刊-开放研究》上发表了关于SM17的临床前研究,突显了其治疗CRSwNP和IPF的潜力。这些结果表明SM17是一种极具前景的潜在同类首创生物制剂,靶向关键的上游警报素(IL-25)。通过同时靶向Th2炎症、Th17分化和纤维化,SM17可能为CRSwNP和IPF提供一种多方面的治疗策略,有潜力填补当前针对下游效应器疗法存在局限性的未满足需求。

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