Janux Therapeutics Inc. announced the dosing of the first participant in a Phase 1 clinical study of JANX011, a CD19-targeted bispecific engineered using the company's Adaptive Immune Response Modulator $(ARM)$ platform. The study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of JANX011 in healthy adult volunteers, with a focus on immune effects such as B-cell depletion and memory B-cell reset. Results from the study have not yet been presented and are expected to inform future clinical development.
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