Delivered 41% revenue growth and 83% gross margin in Q4 2025;
Improved Net Loss by 52% and achieved first-ever Adjusted EBITDA positivity in Q4 2025;
FY2026 Revenue Guidance of $106-112 million, mid-point reflects 23% growth;
Conference Call and Webcast Today at 4:30 p.m. ET
LOUISVILLE, Colo., Feb. 26, 2026 (GLOBE NEWSWIRE) -- Biodesix, Inc. (Nasdaq: BDSX), a leading diagnostic solutions company, today announced its financial and operating results for the fourth quarter and year ended December 31, 2025 (fiscal 2025).
"Biodesix delivered exceptional results in the fourth quarter, with revenue of $28.8 million and 83% gross margin," said Scott Hutton, Chief Executive Officer. "We exceeded the high end of our revenue guidance by delivering 41% growth, and for the first time ever, achieved Adjusted EBITDA positivity in the quarter demonstrating the strength of our operating leverage and gross margins, which have become a hallmark of Biodesix performance. In 2025, we accelerated the growth of our lung-focused commercial strategy, expanded our pipeline, announced new partnerships, grew our development services offering, and presented clinical data on our on-market and pipeline products."
Business and Financial Highlights for the Fourth Quarter and Full Year 2025
-- Diagnostic Tests core organic revenue, excluding collection on claims
older than one year, was $24.1 million in the fourth quarter, growth of
40% over the prior year comparable period, driven by test volume growth
of 23% and increased average revenue per test;
-- Diagnostic Test revenue of $25.1 million and $79.2 million for the
fourth quarter and fiscal 2025, respectively, an increase of 46%
and 22% over the prior year comparable periods. Test volumes were
18,000 and 62,600 for the fourth quarter and fiscal 2025,
respectively, an increase of 23% and 15% over the prior year
comparable periods. The increase in average revenue per test was
driven by additional payer coverage, improvements in revenue cycle
management, and approximately $1.0 million in collections from
claims older than one year;
-- Development Services revenue of $3.6 million and $9.3 million for the
fourth quarter and fiscal 2025, respectively, an increase of 12% and 41%
over the respective prior year comparable periods, a result of both
delivering against the Company's book of contracted business and securing
new agreements;
-- Total revenue of $28.8 million in the fourth quarter and $88.5 million in
fiscal 2025, an increase of 41% and 24% over the respective prior year
comparable periods, with gross margin expanding 400bps to 83% in the
fourth quarter and 300bps to 81% in fiscal 2025;
-- Improvements in gross margin percentage were driven by growth in
Diagnostic testing, improvements in average revenue per test, and
optimization of testing workflows that resulted in decreases in
costs per test;
-- Operating expenses (excluding direct costs and expenses) of $25.8 million
and $99.7 million for the fourth quarter and fiscal 2025, an increase of
14% and 10% over the respective prior year comparable periods. Sales,
marketing, and general administrative investment increased 14% to support
the 41% revenue growth delivered in the fourth quarter. The Company
expects continued operating leverage as our expanded sales team advances
along the productivity curve and converts growing experience into
sustained performance;
-- Includes non-cash stock compensation expense of $1.1 million and
$4.1 million during the fourth quarter and fiscal 2025, a decrease
of 15% and 38% over the respective prior year comparable periods;
-- Net loss of $4.0 million and $35.3 million for the fourth quarter and
fiscal 2025, an improvement of 52% and 18% over the respective prior year
comparable periods;
-- Adjusted EBITDA of $0.5 million in Q4 2025, the Company's first quarter
of Adjusted EBITDA positivity, representing a $4.5 million or 113%
improvement from Q4 2024. This milestone reflects strong revenue
flow-through and operating leverage across Biodesix. Adjusted EBITDA for
fiscal 2025 was a loss of $17.5 million, an improvement of 21% over
fiscal 2024;
Metric FY25 Guidance (Raised) FY25 Actual Result
------------------ ---------------------- ---------------- --------------
Total Revenue $84-86M $88.5M Above High End
------------------ ---------------------- ---------------- --------------
Q4 Adj. EBITDA Positive in Q4 $0.5M (positive) First-Ever
------------------ ---------------------- ---------------- --------------
Gross Margin (FY) 78% - 79% 81% +300bps YoY
------------------ ---------------------- ---------------- --------------
-- Pro forma cash and cash equivalents of $33.7 million (including
subsequent ATM proceeds), supported by the Company's first quarter of
Adjusted EBITDA positivity, which positions Biodesix to reduce quarterly
cash consumption as revenue scales;
-- Cash and cash equivalents of $19.0 million as of December 31, 2025
was inclusive of $2.3 million in at-the-market proceeds, and
subsequent to the end of the quarter, the Company raised and
additional $14.7 million to support continued growth investment;
-- Subsequent to the end of the quarter, the Company amended the
Senior Secured Term Loan with Perceptive Advisors to extend the
maturity date and interest only period to November 2028. The
extension and additional cash strengthens the balance sheet and
provides increased financial flexibility.
2026 Financial Outlook
The Company anticipates generating between $106-112 million in total revenue in 2026, the mid-point representing 23% growth over 2025 total revenue, and expects continued improvement toward sustained Adjusted EBITDA positivity. The revenue growth and improvement on the path to profitability is expected to be driven by the increasing productivity across our expanded sales organization, improvements to average revenue per test demonstrated in the second half of 2025, additional clinical data on the Nodify Lung tests to help drive adoption from healthcare providers and payers, increases in Development Services pipeline, and the demonstrated operating leverage.
Metric FY 2025 Actual FY 2026 Guidance ------------- -------------- ---------------------------------------------- Total Revenue $88.5M $106-112M (mid-point is 23% growth) ------------- -------------- ---------------------------------------------- Gross Margin 81% Maintain 80% ------------- -------------- ---------------------------------------------- Adj. EBITDA $(17.5)M FY Continued improvement on path to profitability ------------- -------------- ----------------------------------------------
Conference call and webcast information
Listeners can register for the webcast via this link. Analysts who wish to participate in the question-and-answer session should use this link. A replay of the webcast will be available via the Company's investor website approximately two hours after the call's conclusion. Participants are advised to join 15 minutes prior to the start time.
For a full list of Biodesix press releases and webinars, please visit biodesix.com.
About Biodesix
Biodesix is a leading diagnostic solutions company, driven to improve clinical care and outcomes for patients. Biodesix Diagnostic Tests, marketed as Nodify Lung$(R)$ Nodule Risk Assessment and IQLung(R) Cancer Treatment Guidance, support clinical decisions to expedite personalized care and improve outcomes for patients with lung disease. Biodesix Development Services enable the world's leading biopharmaceutical, life sciences, and research institutions with scientific, technological, and operational capabilities that fuel the development of diagnostic tests, tools, and therapeutics. For more information, visit biodesix.com.
Trademarks: Biodesix, Biodesix Logo, Nodify Lung, and IQLung are trademarks or registered trademarks of Biodesix, Inc.
Use of Non-GAAP Financial Measure
Biodesix reported results are presented in accordance with generally acceptedaccounting principles in the United States (GAAP). Biodesix has provided in this press release financial information that has not been prepared in accordance with GAAP. Biodesix uses the non-GAAP financial measure, Adjusted EBITDA, internally in analyzing its financial results and believes that use of this non-GAAP financial measure is useful to investors as an additional tool to evaluate ongoing operating results and trends and in comparing Biodesix financial results with other companies in its industry, many of which present similar non-GAAP financial measures. Non-GAAP financial measures are not meant to be considered in isolation or as a substitute for comparable GAAP financial measures and should be read only in conjunction with Biodesix financial statements prepared in accordance with GAAP. A reconciliation of Biodesix historical non-GAAP financial measure to the most directly comparable GAAP measure has been provided in the financial statement tables included in this press release, and investors are encouraged to review the reconciliation.
Adjusted EBITDA is a key performance measure that our management uses to assess our financial performance and is also used for internal planning and forecasting purposes. We believe that this non-GAAP financial measure is useful to investors and other interested parties in analyzing our financial performance because it provides a comparable overview of our operations across historical periods. In addition, we believe that providing Adjusted EBITDA, together with a reconciliation of Net loss to Adjusted EBITDA, helps investors make comparisons between our Company and other companies that may have different capital structures, different tax rates, and/or different forms of employee compensation.
Adjusted EBITDA is used by our management team as an additional measure of our performance for purposes of business decision-making, including managing expenditures. Period-to-period comparisons of Adjusted EBITDA help our management identify additional trends in our financial results that may not be shown solely by period-to-period comparisons of Net loss or Loss from operations. Our management recognizes that Adjusted EBITDA has inherent limitations because of the excluded items and may not be directly comparable to similarly titled metrics used by other companies.
We calculate Adjusted EBITDA as Net loss adjusted to exclude interest, income tax expense, if any, depreciation and amortization, share-based compensation expense, loss on debt extinguishments, net, change in fair value of warrant liabilities, net, other income, net, and other non-recurring items. Non-recurring items are excluded as they are not representative of our underlying operating performance. Adjusted EBITDA should be viewed as a measure of operating performance that is a supplement to, and not a substitute for Loss from operations, Net loss, and other GAAP measures.
Note Regarding Forward-Looking Statements
This press release may contain forward-looking statements that involve substantial risks and uncertainties for purposes of the safe harbor provided by the Private Securities Litigation Reform Act of 1995. All statements contained in this press release other than statements of historical fact, are forward-looking statements. The words "believe," "may," "will," "estimate," "continue," "anticipate," "intend," "plan," "expect," "predict," "potential," "opportunity," "goals," or "should," and similar expressions are intended to identify forward-looking statements. Such statements are based on management's current expectations and involve risks and uncertainties. Actual results and performance could differ materially from those projected in the forward-looking statements as a result of many factors. Biodesix has based these forward-looking statements largely on its current expectations and projections about future events and trends. These forward-looking statements are subject to a number of risks, uncertainties, and assumptions.Forward-looking statements may include information concerning possible or assumed future results of operations, including descriptions of our revenues, profitability, outlook, and overall business strategy, the timing and assumptions regarding collection of revenues on projections, availability of funds and future capital, the anticipated impact and benefits of new clinical data, reimbursement coverage and research partnerships, the impact of enhanced U.S. tariffs, import/export restrictions or other trade barriers on the company and its operations and financial performance. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified. Other factors that could cause actual results to differ materially from those contemplated in this press release can be found in the Risk Factors section of our most recent Annual Report on Form 10-K, filed February 26, 2026. Biodesix undertakes no obligation to revise or publicly release the results of any revision to such forward-looking statements, except as required by law. Given these risks and uncertainties, readers are cautioned not to place undue reliance on such forward-looking statements. All forward-looking statements are qualified in their entirety by this cautionary statement.
Contacts:
Media:
Natalie St. Denis
natalie.stdenis@biodesix.com
(720) 925-9285
Investors:
Chris Brinzey
chris.brinzey@icrhealthcare.com
(339) 970-2843
Biodesix, Inc.
Condensed Balance Sheets (unaudited)
(in thousands, except share data)
December 31, 2025 December 31, 2024
------------------- -------------------
Assets
Current assets
Cash and cash
equivalents $ 18,987 $ 26,245
Accounts receivable,
net of allowance for
credit losses of $62
and $481 9,036 8,603
Other current assets 4,495 4,636
--------------- ---------------
Total current assets 32,518 39,484
Non-current assets
Property and equipment,
net 24,817 27,828
Intangible assets, net 3,883 5,874
Operating lease
right-of-use assets 2,997 1,767
Goodwill 15,031 15,031
Other long-term assets 8,230 7,260
--------------- ---------------
Total non-current
assets 54,958 57,760
--------------- ---------------
Total assets $ 87,476 $ 97,244
=============== ===============
Liabilities and Stockholders' (Deficit) Equity
Current liabilities
Accounts payable $ 3,080 $ 2,194
Accrued liabilities 11,033 10,064
Deferred revenue 961 678
Current portion of
operating lease
liabilities 1,364 719
Current portion of
notes payable 6 21
Other current
liabilities 992 641
--------------- ---------------
Total current
liabilities 17,436 14,317
Non-current liabilities
Long-term notes
payable, net of
current portion 47,445 36,408
Long-term operating
lease liabilities 24,039 24,828
Other long-term
liabilities 1,021 815
--------------- ---------------
Total non-current
liabilities 72,505 62,051
--------------- ---------------
Total liabilities 89,941 76,368
Commitments and
contingencies
Stockholders' (deficit)
equity
Preferred stock,
$0.001 par value,
5,000,000 authorized;
0 (2025 and 2024)
issued and
outstanding -- --
Common stock, $0.001
par value, 200,000,000
authorized; 8,253,053
(2025) and 7,274,578
(2024) shares issued
and outstanding 8 7
Additional paid-in
capital 495,289 483,366
Accumulated deficit (497,762) (462,497)
--------------- ---------------
Total stockholders'
(deficit) equity (2,465) 20,876
--------------- ---------------
Total liabilities and
stockholders' (deficit)
equity $ 87,476 $ 97,244
=============== ===============
Biodesix, Inc.
Condensed Statements of Operations (unaudited)
(in thousands, except per share data)
Three Months Ended Year Ended December
December 31, 31,
------------------- -------------------
2025 2024 2025 2024
------- --------- -------- --------
Revenues
Diagnostic Tests $25,148 $ 17,205 $ 79,197 $ 64,708
Development
Services 3,607 3,224 9,302 6,615
------ -------- ------- -------
Total revenues 28,755 20,429 88,499 71,323
Direct costs and
expenses 4,879 4,342 16,719 15,573
Research and
development 2,870 2,414 12,001 9,559
Sales,
marketing,
general and
administrative 22,972 20,219 87,545 80,451
Impairment loss
on intangible
assets 1 103 107 238
------ -------- ------- -------
Total operating
expenses 30,722 27,078 116,372 105,821
------ -------- ------- -------
Loss from
operations (1,967) (6,649) (27,873) (34,498)
Other (expense)
income:
Interest expense (2,059) (1,752) (7,716) (8,258)
Loss on
extinguishment
of liabilities -- -- -- (248)
Change in fair
value of
warrant
liability, net -- -- (280) --
Other income,
net 46 150 604 73
------ -------- ------- -------
Total other expense (2,013) (1,602) (7,392) (8,433)
Net loss $(3,980) $ (8,251) $(35,265) $(42,931)
====== ======== ======= =======
Net loss per share,
basic and diluted $ (0.49) $ (1.13) $ (4.67) $ (6.64)
Weighted-average
shares
outstanding, basic
and diluted 8,065 7,330 7,551 6,470
Biodesix, Inc.
Reconciliation of Net Loss to Adjusted EBITDA (unaudited)
(in thousands)
Three Months Ended Year Ended December
December 31, 31,
------------------- -------------------
2025 2024 2025 2024
------- --------- -------- --------
Net loss $(3,980) $ (8,251) $(35,265) $(42,931)
Interest
expense 2,059 1,752 7,716 8,258
Depreciation
and
amortization 1,387 1,449 5,670 5,773
Share-based
compensation
expense 1,075 1,265 4,139 6,638
Loss on
extinguishment
of
liabilities -- -- -- 248
Change in fair
value of
warrant
liability, net -- -- 280 --
Other income,
net (11) (150) (10) (73)
------ -------- ------- -------
Adjusted EBITDA $ 530 $ (3,935) $(17,470) $(22,087)
====== ======== ======= =======
(END) Dow Jones Newswires
February 26, 2026 16:01 ET (21:01 GMT)