XtalPi Holdings Ltd. reported that ReviR Therapeutics has dosed the first participant in a Phase 1 randomized, double-blind, placebo-controlled, dose-escalation trial of RTX-117, an investigational small molecule for Charcot-Marie-Tooth disease and Vanishing White Matter disease. The study, being conducted in China, is designed to assess safety, tolerability, pharmacokinetics and pharmacodynamics in healthy participants, with the aim of supporting future patient studies. The announcement did not include clinical results; results are expected to be generated in the future as the trial progresses.
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